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Blog posts tagged with 'wound healing'

Improving functional outcomes of great toe amputations
Improving functional outcomes of great toe amputations

Wounds of the lower extremity have a host of different contributing causes, but in diabetic patients, the vast majority ofDiabetes - great toe amputation wounds occur as a result of loss of protective sensation.  Protective sensation is the ability to feel pain.  Diabetic peripheral neuropathy results in loss of sensation, inabil...

Wounds and wound prevention in the feet
Wounds and wound prevention in the feet

Managing foot wounds in the decompensated patient.Diabetic foot care

One of the greatest challenges in foot care is wound prevention and wound management.  Wounds come in all shapes and sizes, but there’s always one common denominator in wound care; a decompensated patient.  What is a decompensated patient?  A decom...

Does methotrexate influence wound healing?
Does methotrexate influence wound healing?

Methotrexate is an antimetabolite that works by inhibiting dihydrofolic reductase. This enzyme is important in the production of DNA. Methotrexate targets rapidly growing cells such as inflammatory cells in rheumatoid arthritis or psoriasis. Methotrexate was originally used as a cancer drug for malignancies including acute lymphoblastic leukemia and lymphomas.