Managing foot wounds in the decompensated patient.

One of the greatest challenges in foot care is wound prevention and wound management.  Wounds come in all shapes and sizes, but there’s always one common denominator in wound care; a decompensated patient.  What is a decompensated patient?  A decom...

Methotrexate is an antimetabolite that works by inhibiting dihydrofolic reductase. This enzyme is important in the production of DNA. Methotrexate targets rapidly growing cells such as inflammatory cells in rheumatoid arthritis or psoriasis. Methotrexate was originally used as a cancer drug for malignancies including acute lymphoblastic leukemia and lymphomas.